SIGNITEF (eye drops): instructions for use, description, composition and reviews
In what dosage is prescribed the medicine "Signyceph"(eye drops)? Instructions for use, price and indications of the drug will be presented in this article. Also in it you will find information about what the patients say about this tool, whether it has analogs, side effects and contraindications.
Composition, description and packaging
The preparation "Signtsef" (eye drops), instructionon the application of which is enclosed in a cardboard package, contains an active substance such as levofloxacin hemihydrate. As additional components use sodium chloride, hydrochloric acid, benzalkonium chloride, hypromellose, sodium hydroxide and water.
For sale, the drug in question as a clear liquid of light yellow color comes in a dropper bottle made of plastic.
Pharmacodynamics of the preparation
How does the medicine "Signtsef" (eye drops) work? The instruction for use states that the said preparation is an antimicrobial and antibacterial agent.
Its active substance inhibits topoisomerase IVand DNA-gyrase, and also inhibits the synthesis of DNA, prevents cross-linking of gaps and supercoiling of DNA. It should also be said that the drug in question can provoke morphological changes in the cytoplasm, membranes and cell walls of bacteria.
Eye drops have a harmful effect on both gram-positive and gram-negative aerobes. In addition, they are active against Chlamydia trachomatis.
After using the drug, its active ingredientaccumulates in a tear film. At the same time, the concentration of the drug substance in the tear fluid quickly reaches high values and lasts for six hours.
At what diseases should I use the medicine "SIGNITEF" (drops)? Instructions for use, reviews of ophthalmologists say that the drug in question is often used when:
- treatment of anterior segment infections and an adnexa, which was triggered by bacteria that are susceptible to levofloxacin;
- the need for prophylactic measures after operations before the eyes;
- local therapy for infectious eye diseases that were provoked by bacteria susceptible to levofloxacin.
Contraindications to the use of eye drops
What kind of contraindications do you need to know before using SIGNITSEF (eye drops)? Instruction for use states that this medication is prohibited when:
- defeats of tendons;
- hypersensitivity to the elements of the drug;
- previously conducted treatment with quinolones;
Also, do not use eye drops for infusion. With caution this drug is prescribed in childhood.
"Signtsef" (eye drops): instruction
The prices and analogues of the medicament in question will be presented at the end of the article.
The instruction informs that the given preparation followsbegin to apply within the first two days after the appearance of signs of the disease. The drug is instilled in the infected eyes in an amount of 1-2 drops at intervals of 120 minutes.
The maximum frequency of this medication is 8 times a day. In 2 days after the beginning of treatment the drug is started to be applied in the same dose, but already 4 times a day.
The duration of therapy directly depends on the characteristics and severity of the disease. Usually treatment lasts for 5 days.
Before applying drops to the patient, the head should be turned back, and then the lower eyelid should be pulled back. It should be dripped with a medicine, and then for a few minutes to close your eyes.
To prevent the drug from getting into the tear duct, the inner edge of the optic organ should be pressed with your finger and kept in this condition for 1-2 minutes. At the same time it is forbidden to blink.
As for the remnants of eye drops, they are removed with a clean cloth, but without contact with the eyes.
Side effects on the background of applicationthe drug in question is extremely rare. As a rule, such reactions are characterized by moderate or low severity and after some time pass independently.
So what are the undesirable effects caused by"SIGNITSEF" medication? Instructions for use (the description of the drops above) indicates that the agent may provoke the appearance of the following ophthalmic disorders:
- burning in the eyes, matting eyelids, deterioration of visual acuity;
- pain in the eyes, papillary reaction of the conjunctiva, edema of the eyelids;
- conjunctival follicles, pruritus, erythema eyelid, conjunctival infection;
- chemosis, photophobia, dry eyes.
Sometimes on the part of the immune system, anaphylactic and allergic reactions are observed in patients.
As for the central nervous system, with itsthe sides may experience dizziness, drowsiness, headaches, paresthesia, confusion, fear, weakness, movement disorders, anxiety, insomnia, depression, hallucinations and convulsions.
Also, rhinitis, thoracic and mediastinal disorders can occur.
Cases of overdose
With the occasional administration of eye drops, toxic effects on the body are excluded. This is due to the fact that the amount of levofloxacin in the preparation is too low.
If a local overdose has occurred, the patient may experience increased adverse reactions. In this case, the drug should be discontinued and the eyes thoroughly rinsed with warm water.
"SIGNITSEF" reduces effectivenessdrugs that inhibit bowel motility, as well as aluminum-containing and magnesium-containing antacid drugs, sucralfate and iron salts. The interval between the use of these medicines should be two hours.
The droplets in question increase the half-life of "Cyclosporine."
Removal of levofloxacin is significantly slowed by simultaneous use of drugs that inhibit tubular secretion, and "Cimetidine."
Eye drops "SIGNITSEF" is not recommended for use during the wearing of soft contact lenses due to the presence in the preparation of the preservative benzalkonium chloride.
To avoid getting dirt in the bottle, do not allow the dropper contact with mucous eyes.
Price, similar preparations
The average cost of the funds in question is about 220 rubles.
As for similar drugs, they include the following: Oftakvix, Glevo, Lebel, Levobaks, Levogrin, Levolety, Levotor, Levofast, Loksof, Novoks , "Remedy", "Floksium."
Reviews of eye drops
Eye drops "SIGNITSEF" (instruction, price, reviews described in this article) are a very popular drug. Reviews about them are mostly positive.
Patients talk about the high effectiveness of the solution. He treats infectious diseases of the eye quite quickly, and is also great for prevention.
Among the negative responses are those in which patients complain about the high cost of medication and the inability to use it during breastfeeding and when carrying a child.